gabaa receptor agonist muscimol (MedChemExpress)
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Gabaa Receptor Agonist Muscimol, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/gabaa+receptor+agonist+muscimol/Muscimol/pm41616926-44-1-6
Average 97 stars, based on 10 article reviews
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![Figure 2. Monitoring acute changes in [Cl]i with SClm. A, Two-photon image of CA1 pyramidal neurons in the hippocampus of an acute slice from a SClm mouse. A patch pipette (in white) is attached to cell #1 for a whole-cell recording. Two control cells are indi- cated with #2 and #3. Scale bar: 20 mm. B, Time course of CFP (upper row) and YFP (lower row) fluorescence right before and dur- ing the first minutes after break-in. After break-in (0’; gray) cell #1 rapidly fills with the high chloride internal solution (70 mM KCl) resulting in a decrease in YFP fluorescence. Scale bar: 20 mm. C, Average FRET ratio over time for cells that were infused with 70 mM KCl (n = 2), and neighboring control cells (n = 4). Error bars represents SEM. D, Acute wash-in with <t>muscimol</t> in cultured slices with viral SClm expression caused a decrease in FRET ratio in CA1 pyramidal neurons within 10 min. Scale bar: 20 mm. E, Average FRET ratios over time during wash-in of muscimol (gray area) and control. Data from 84 cells, 7 slices, 4 mice in both groups.](https://doi-unpaywalled-images-cdn.bioz.com/1149/10__1523_slash_eneuro__0416___22__2022/10__1523_slash_eneuro__0416___22__2022____page5_image1.jpg)